Highlights from the “First Annual” GI CME Event, 7/28/18

Though certainly not the first in the history of the division, Saturday’s Update in Gastroenterology, Hepatology and Endoscopy event was the first Continuing Medical Education event for the Division of Gastroenterology and Hepatology in more than a decade. That was more than enough time to merit the “First Annual” addition to the day-long conference’s title. […]

Vascular and Neural Complications in Type 2 Diabetic Rats: Improvement by Sacubitril/Valsartan Greater Than Valsartan Alone

Article: Vascular and Neural Complications in Type 2 Diabetic Rats: Improvement by Sacubitril/Valsartan Greater Than Valsartan Alone Authors: Eric P. Davidson, Lawrence J. Coppey, Hanna Shevalye, Alexander Obrosov and Mark A. Yorek Journal: Diabetes. 2018 Aug;67(8):1616-1626 Abstract: Previously, we had shown that a vasopeptidase inhibitor drug containing ACE and neprilysin inhibitors was an effective treatment […]

Ultrasound Symposium Continues to Grow

The University of Iowa has now crossed the halfway mark when it comes to hosting this event. Three of the six times the Midwest Fellows Critical Care Ultrasound Symposium has met, they have done so in Iowa City. There are a lot of good reasons for this, not least of which is that Iowa is […]

Dayal Receives AHA Award to Study Gut Microbiome

Sanjana Dayal, PhD, Assistant Professor of Internal Medicine, has received a two-year, $200,000 Innovative Project Award (IPA) from the American Heart Association. Dr. Dayal and her research team will investigate how aging-related changes in the gut microbiome affect thrombosis. This novel study will also examine how the antioxidant glutathione peroxidase 1 (Gpx1) alters the gut […]

Grumbach Receives AHA Grant to Study Microvessel Damage

Isabella Grumbach, MD, Professor in Cardiovascular Medicine, has received a two-year, $200,000 Innovative Project Award from the American Heart Association. In a project titled “New models of radiation endotheliopathy,” Dr. Grumbach will investigate the effects or radiation on small blood vessels. Specifically, she and her colleagues will employ new technologies to examine vasculature in the […]

Adams Renews VA Merit Award

Chris Adams, MD, PhD, Professor of Internal Medicine and Molecular Physiology & Biophysics, has successfully renewed a four-year, $650,000 VA Merit Award. Dr. Adams and his colleagues will use this renewal to continue their investigations of age-related skeletal muscle atrophy, or sarcopenia. Specifically, they will build on the previous grant’s work, which resulted in the […]

Discovery of an Experimental Model of Unicuspid Aortic Valve

Article: Discovery of an Experimental Model of Unicuspid Aortic Valve Authors: Robert M. Weiss, Yi Chu, Robert M. Brooks, Donald D. Lund, Justine Cheng, Kathy A. Zimmerman, Melissa K. Kafa, Phanicharan Sistla, Hardik Doshi, Jian Q. Shao, Ramzi N. El Accaoui, Catherine M. Otto, Donald D. Heistad Journal: J Am Heart Assoc. 2018 Jun 30;7(13) […]

Wellness and Community Engagement

Health care providers face some of the greatest levels of stress of any profession. Though this may occur for understandable reasons, our chosen responsibilities do not diminish the necessity we have to also care for ourselves. In fact, multiple studies show that we have a greater susceptibility to depression, fatigue, anxiety, sleep deprivation, and many […]

CES Inaugural Drive Focuses on Students

The members of the Department of Internal Medicine’s Community Engagement & Services (CES) committee are launching our inaugural program in support of the Iowa City Community School District (ICCSD). We are asking everyone to help Iowa City students start off the school year supplied for success. Below is a wish list of new school supplies […]

Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency

Article: Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency Authors: Colleen S. Stein, Pooja Jadiya, Xiaoming Zhang, Jared M. McLendon, Gabrielle M. Abouassaly, Nathan H. Witmer, Ethan J. Anderson, John W. Elrod, Ryan L. Boudreau Journal: Cell Rep. 2018 Jun 26;23(13):3710-3720.e8 Abstract: Mitochondria are composed of many small proteins that control protein […]