Magnetic diabetes treatment attracts NIH funding

“The more we look, the more the transfer of electrons seems to underlie diabetes,” postdoctoral research Calvin Carter, PhD, said in a Q&A with the American Diabetes Association (ADA). That search was borne out last fall, when Carter and MD/PhD student Sunny Huang, PhD, published ground-breaking findings in Cell Metabolism, showing that static electric and […]

Decreasing ceramides reduced obesity, insulin resistance in mice

Thermogenic adipocytes are specialized cells capable of converting chemical energy into heat and regulating body temperature. However, aging and weight gain can deplete thermogenic adipocytes and increase insulin resistance. Bhagirath Chaurasia, PhD, assistant professor in Endocrinology and Metabolism, aimed to determine the mechanisms behind this correlation in a study recently published in Molecular Metabolism. “Thermogenic adipocyte quantity […]

Li earns AHA career development award

Qiuxia (Lisa) Li, PhD, associate in Cardiovascular Medicine, received a three-year, $231,000, Career Development Award from the American Heart Association (AHA). Li will use this funding to investigate how Sirtuin1 in endothelium affects peripheral insulin-sensitive tissues. “Endothelial dysfunction and inflammation is a risk factor for cardiovascular diseases and co-exists with insulin resistance,” Li said. “Sirtuin1 […]

Dokun brings PAD research to Iowa

Before he joined the University of Iowa and became Division Director of Endocrinology and Metabolism, Associate Professor Ayotunde Dokun, MD, PhD, FACE, was principal investigator on a five-year, $1.93M R01 from the National Heart, Lung, and Blood Institute. That NIH grant has traveled with him from Tennessee to Iowa where his work continues investigating possible […]

Links between type 2 diabetes and lipid mobilization point to new treatment target

Yumi Imai, MD, associate professor in Endocrinology and Metabolism, received a four-year, $710,000 VA Merit Award. With this new grant, Imai will build on previous research to investigate type 2 diabetes treatment by identifying correlations between lipolysis and beta cell dysfunction.  “Type 2 diabetes is the major health problem with high prevalence in the US, inflicting […]

Koo explores links between liver disease and diabetes

Nonalcoholic fatty liver disease (NAFLD) has increasingly become a concern for people with diabetes and the providers who care for them. NAFLD causes insulin resistance in the liver, which plays a large role in the development of the diabetes. Young Do Koo, PhD, Postdoctoral Research Scholar in the Abel Lab, received a three-year Postdoctoral Fellowship […]

Stephens advances diabetes research with pair of grants

Sam Stephens, PhD, assistant professor in Endocrinology and Metabolism, recently earned a $1.2M grant from the Department of Defense’s (DOD) Congressionally Directed Medical Research Program (CDMRP). Additionally, Dr. Stephens received a three-year, $345,000 Innovative Basic Science Award from the American Diabetes Association (ADA). The projects for each of these grants focus on understanding insulin packaging […]

Abel to lead one of four AHA research networks

E. Dale Abel, MD, PhD, will be awarded a four-year $3.8M grant from the American Heart Association (AHA) to investigate mechanisms that increase the risk of cardiovascular disease in people with type 2 diabetes. Abel will oversee a Strategically Focused Research Network (SFRN) of three projects in partnership with other UI departments and the Massachusetts […]

Diabetes research enters “the matrix”

Coming soon to a public television stations across the country! Hosted by the television and film actor Laurence Fishburne, the program Information Matrix profiles innovative and exceptional organizations and individuals. An episode titled “Reversing Diabetes” brought a film crew to Iowa City in order to document the work being done within the Fraternal Order of […]

53rd Annual Internal Medicine Research Day, 10/15/19

Since the tradition began in the early 1960s, Research Day has seen a variety of formats. But what has always been at its core was the celebration of the diversity and depth of the work being done by a panoply of trainees, clinicians, and basic scientists. Better understanding a disease mechanism or testing a new […]