Intratumoral talimogene laherparepvec injection with concurrent preoperative radiation in patients with locally advanced soft-tissue sarcoma of the trunk and extremities: phase IB/II trial

Article: Intratumoral talimogene laherparepvec injection with concurrent preoperative radiation in patients with locally advanced soft-tissue sarcoma of the trunk and extremities: phase IB/II trial Authors: Varun Monga, Benjamin J Miller, Munir Tanas, Sarag Boukhar, Bryan Allen, Carryn Anderson, Laura Stephens, Stacey Hartwig, Steven Varga, Jon Houtman, Lei Wang, Weizhou Zhang, Omar Jaber, Jon Thomason, David […]

Utility of high resolution mapping to guide ablation of ventricular arrhythmias from the aortic sinuses of Valsalva

Article: Utility of high resolution mapping to guide ablation of ventricular arrhythmias from the aortic sinuses of Valsalva Authors: Faisal Matto, Dev Venugopal, Prashant D Bhave, Troy E Rhodes, Alexander Mazur Journal: J Interv Card Electrophysiol. 2021 Aug 7. doi: 10.1007/s10840-021-01040-9. Online ahead of print. Abstract: Purpose: Left ventricular outflow tract (LVOT) arrhythmias are commonly […]

Polgreen, Miller’s work named among ‘Best Research Papers’

Senior author Phil Polgreen, MD, MPH, professor in the Division of Infectious Diseases, has received a “Best Research Paper Award” from the University of Iowa Carver College of Medicine as part of its new initiative to highlight innovative biomedical research. Aaron Miller, PhD, research assistant professor of Infectious Diseases, is the paper’s lead author. The […]

Mitochondrial Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet β-Cell Function

Article: Mitochondrial Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet β-Cell Function Authors: Casey J Bauchle, Kristen E Rohli, Cierra K Boyer, Vidhant Pal, Jonathan V Rocheleau, Siming Liu, Yumi Imai, Eric B Taylor, Samuel B Stephens Journal: Diabetes. 2021 Aug;70(8):1717-1728 Abstract: The defining feature of pancreatic islet […]

PKM2 promotes neutrophil activation and cerebral thrombo-inflammation: Therapeutic implications for ischemic stroke

Article: PKM2 promotes neutrophil activation and cerebral thrombo-inflammation: Therapeutic implications for ischemic stroke Authors: Nirav Dhanesha, Rakesh B Patel, Prakash Doddapattar, Madankumar Ghatge, Gagan D Flora, Manish Jain, Daniel Thedens, Heena Olalde, Mariia Kumskova, Enrique Leira, Anil K Chauhan Journal: Blood. 2021 Sep 15;blood.2021012322. doi: 10.1182/blood.2021012322. Online ahead of print. Abstract: There is a critical […]

Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer

Article: Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer Authors: Justin Chau, Meeta Yadav, Ben Liu, Muhammad Furqan, Qun Dai, Shailesh Shahi, Arnav Gupta, Keri Nace Mercer, Evan Eastman, Taher Abu Hejleh , Carlos Chan, George J Weiner, Catherine Cherwin, Sonny T M […]

Individualized coaching in health system-wide provider communication training

Article: Individualized coaching in health system-wide provider communication training Authors: Kipton Pedersen, Theresa M H Brennan, Alexander D Nance, Marcy E Rosenbaum Journal: Patient Educ Couns. 2021 Jun 30;S0738-3991(21)00422-5. doi: 10.1016/j.pec.2021.06.023. Online ahead of print. Abstract: Objectives: Most practicing health professionals lack communication skills training (CST). Increasingly health care systems have implemented CST programs, mainly […]

Gastric Bypass Sensitizes Sympathetic and Thermogenic Activity of Brown Adipose Tissue to Cold Exposure

Article: Gastric Bypass Sensitizes Sympathetic and Thermogenic Activity of Brown Adipose Tissue to Cold Exposure Authors: Yi Chu, Liping Tian, Hussein Herz, Benjamin Linden, Donald A Morgan, Meghan C Naber, Matthew Potthoff, Kamal Rahmouni, Mohamad Mokadem Journal: Obes Surg. 2021 Jul 15. doi: 10.1007/s11695-021-05560-1. Online ahead of print. Excerpt: Multiple previous animal studies showed that […]

Inhaled Medication Use in Smokers With Normal Spirometry

Article: Inhaled Medication Use in Smokers With Normal Spirometry Authors: Nicholas R Arnold, Emily S Wan, Craig P Hersh, Andrei Schwartz, Greg Kinney, Kendra Young, John Hokanson, Elizabeth A Regan, Alejandro P Comellas, Spyridon Fortis Journal: Respir Care. 2021 Apr;66(4):652-660. Abstract: Background: The objective of our study was to identify variables associated with inhaled medication […]