Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging

Article: Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging Authors: Courtney Yong, Devon L Moose, Nadine Bannick, Wade R Gutierrez, Marion Vanneste, Robert Svensson, Patrick Breheny, James A Brown, Rebecca D Dodd, Michael B Cohen, Michael D Henry Journal: PLoS One. 2020 Sep […]

Remote Triage by Nurse Practitioners Was Associated With Fewer Subsequent Face

Article: Remote Triage by Nurse Practitioners Was Associated With Fewer Subsequent Face Authors: Peter J Kaboli, Matthew R Augustine, Danielle E Rose, Neetu Chawla, Maria Bouchard, Paul Hebert Journal: J Gen Intern Med. 2021 Jan 26;1-8.  doi: 10.1007/s11606-020-06536-0.  Online ahead of print. Abstract:  Background: In 2015, the Veterans Health Administration (VHA) incorporated nurse practitioners (NPs) into remote triage call centers to supplement […]

Association of Glycolysis-Enhancing α-1 Blockers With Risk of Developing Parkinson Disease

Article: Association of Glycolysis-Enhancing α-1 Blockers With Risk of Developing Parkinson Disease Authors: Jacob E Simmering, Michael J Welsh, Lei Liu, Nandakumar S Narayanan, Anton Pottegård Journal: JAMA Neurol. 2021 Feb 1. doi: 10.1001/jamaneurol.2020.5157. Online ahead of print. Abstract:Importance: Parkinson disease (PD) is a common neurodegenerative disease. A treatment that prevents or delays development of […]

Transformational Changes Between Non-Small Cell and Small Cell Lung Cancer-Biological and Clinical Relevance-A Review

Article: Transformational Changes Between Non-Small Cell and Small Cell Lung Cancer-Biological and Clinical Relevance-A Review Authors: Gerald Clamon, William Zeitler, Josiah An, Taher A Hejleh Journal: Am J Clin Oncol. 2020 Sep;43(9):670-675 Abstract:During the course of therapy, patients with small cell lung cancer have been noted to develop transformation to non-small cell lung cancer and […]

Adipocyte Ceramides-The Nexus of Inflammation and Metabolic Disease

Article: Adipocyte Ceramides-The Nexus of Inflammation and Metabolic Disease Authors: Bhagirath Chaurasia, Chad Lamar Talbot, Scott A Summers Journal: Front Immunol. 2020 Sep 23;11:576347. Abstract:Adipose depots are heterogeneous tissues that store and sense fuel levels. Through the secretion of lipids, cytokines, and protein hormones (adipokines), they communicate with other organ systems, informing them of the […]

Kobayashi finds, treats extremely rare fungal infection

Fungal periprosthetic joint infections (PJI) are essentially unheard of, contributing to only 1% of PJIs. Because they are so rare, fungal PJIs can be hard to identify and treat, leaving physicians without answers for their patients. However, fungal PJI is associated with significant cost and morbidity, especially among immunocompromised patients. Takaaki Kobayashi, MD, third-year fellow in […]

Exposure to Common Geographic COVID-19 Prevalence Maps and Public Knowledge, Risk Perceptions, and Behavioral Intentions

Article: Exposure to Common Geographic COVID-19 Prevalence Maps and Public Knowledge, Risk Perceptions, and Behavioral Intentions Authors: Alistair Thorpe, Aaron M Scherer, Paul K J Han, Nicole Burpo, Victoria Shaffer, Laura Scherer, Angela Fagerlin Journal: JAMA Netw Open. 2021 Jan 4;4(1):e2033538 Excerpt:Several organizations have produced maps showing the prevalence of confirmed coronavirus disease 2019 (COVID-19) […]

In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy

Article: In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy Authors: Yinwen Cheng, Caitlin D Lemke-Miltner, Wattawan Wongpattaraworakul, Zhaoming Wang, Carlos H F Chan, Aliasger K Salem, George J Weiner, Andrean L Simons Journal: J Immunother Cancer. 2020 Oct;8(2):e000940 Abstract:Background: CMP-001 is a novel Toll-like receptor-9 agonist that consists of an unmethylated […]

Preserved Ratio Impaired Spirometry in a Spirometry Database

Article: Preserved Ratio Impaired Spirometry in a Spirometry Database Authors: Andrei Schwartz, Nicholas Arnold, Becky Skinner, Jacob Simmering, Michael Eberlein, Alejandro P Comellas, Spyridon Fortis Journal: Respir Care September 2020, respcare.07712 Abstract:Background: Spirometry results can yield a diagnosis of normal air flow, air flow obstruction, or preserved ratio impaired spirometry (PRISm), defined as a reduced […]

Manuscript Tips: Materials and Methods

The following is the next installment in a series on writing for publication from Kris Greiner, editor in the Design Center. Explore her suite of editing services. As I always recommend, be sure to check any author instructions about the formatting or even the naming of a Materials and Methods (M&M) section. Some journals might ask for this section […]