Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial

Article: Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial Authors: Espen B Ellingsen, Steven O’Day, Artur Mezheyeuski, Agnieszka Gromadka, Trevor Clancy, Timothy S Kristedja, Mohammed Milhem, Yousef Zakharia Journal: Clin Cancer Res. 2023 Aug 15;29(16):3026-3036 Abstract: Purpose: Cancer vaccines represent a novel treatment modality with a […]

The patient perspective on vaccine uptake in adults with psoriasis and eczema

Article: The patient perspective on vaccine uptake in adults with psoriasis and eczema Authors: Megan H Noe, Marjorie Archila, John S Barbieri, Nathaniel Goldman, Christina G Lopez, Arash Mostaghimi, Aaron M Scherer, Alice J Tan, Lourdes M Perez-Chada, Maryam M Asgari, Joel M Gelfand Journal: Arch Dermatol Res. 2023 Aug;315(6):1583-1592 Abstract: Having a chronic disease […]

Effectiveness and Safety of EUS Rendezvous After Failed Biliary Cannulation With ERCP: A Systematic Review and Proportion Meta-analysis

Article: Effectiveness and Safety of EUS Rendezvous After Failed Biliary Cannulation With ERCP: A Systematic Review and Proportion Meta-analysis Authors: Jagpal S Klair, Yousaf Zafar, Munish Ashat, Shivanand Bomman, Arvind R Murali, Mahendran Jayaraj, Joanna Law, Michael Larsen, Dhruv P Singh, Tarun Rustagi, Shayan Irani, Andrew Ross, Richard Kozarek, Rajesh Krishnamoorthi Journal: J Clin Gastroenterol. […]

SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent healthcare-associated infections through hand hygiene: 2022 Update

Article: SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent healthcare-associated infections through hand hygiene: 2022 Update Authors: Janet B Glowicz, Emily Landon, Emily E Sickbert-Bennett, Allison E Aiello, Karen deKay, Karen K Hoffmann, Lisa Maragakis, Russell N Olmsted, Philip M Polgreen, Polly A Trexler, Margaret A VanAmringe, Amber R Wood, Deborah Yokoe, Katherine D Ellingson Journal: Infect […]

Helminth Lessons in Inflammatory Bowel Diseases (IBD)

Article: Helminth Lessons in Inflammatory Bowel Diseases (IBD) Authors: Tyler Atagozli, David E Elliott, Mirac Nedim Ince Journal: Biomedicines. 2023 Apr 18;11(4):1200 Abstract: Helminths are multicellular invertebrates that colonize the gut of many vertebrate animals including humans. This colonization can result in pathology, which requires treatment. It can also lead to a commensal and possibly […]

Mitochondrial pyruvate dehydrogenase kinases contribute to platelet function and thrombosis in mice by regulating aerobic glycolysis

Article: Mitochondrial pyruvate dehydrogenase kinases contribute to platelet function and thrombosis in mice by regulating aerobic glycolysis Authors: Gagan D Flora, Manasa K Nayak, Madankumar Ghatge, Mariia Kumskova, Rakesh B Patel, Anil K Chauhan Journal: Blood Adv. 2023 Jun 13;7(11):2347-2359 Abstract: Resting platelets rely on oxidative phosphorylation (OXPHOS) and aerobic glycolysis (conversion of glucose to […]

DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation

Article: DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation Authors: Athmane Teghanemt, Kara Misel-Wuchter, Jace Heat, Andrew Thurman, Priyanjali Pulipati, Garima Dixit, Ramasatya Geesala, David K Meyerholz, Thorsten Maretzky, Alejandro Pezzulo, Priya D Issuree Journal: EMBO Rep. 2023 May 4;24(5):e55543 Abstract: Regulatory T (T reg) cells developing in the thymus are essential […]

Predicting severe chronic obstructive pulmonary disease exacerbations using quantitative CT: a retrospective model development and external validation study

Article: Predicting severe chronic obstructive pulmonary disease exacerbations using quantitative CT: a retrospective model development and external validation study Authors: Muhammad F A Chaudhary, Eric A Hoffman, Junfeng Guo, Alejandro P Comellas, John D Newell Jr, Prashant Nagpal, Spyridon Fortis, Gary E Christensen, Sarah E Gerard, Yue Pan, Di Wang, Fereidoun Abtin, Igor Z Barjaktarevic, […]

Nephrotoxin Exposure and Acute Kidney Injury in Adults

Article: Nephrotoxin Exposure and Acute Kidney Injury in Adults Authors: Benjamin R Griffin, Linder Wendt, Mary Vaughan-Sarrazin, Hermann Hounkponou  Heather S Reisinger, Stuart L Goldstein, Diana Jalal, Jason Misurac Journal: Clin J Am Soc Nephrol. 2023 Feb 1;18(2):163-172 Abstract: Background: Rates of nephrotoxic AKI are not well described in adults due to lack of a […]

SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent healthcare-associated infections through hand hygiene: 2022 Update

Article: SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent healthcare-associated infections through hand hygiene: 2022 Update Authors: Janet B Glowicz, Emily Landon, Emily E Sickbert-Bennett, Allison E Aiello, Karen deKay, Karen K Hoffmann, Lisa Maragakis, Russell N Olmsted, Philip M Polgreen, Polly A Trexler, Margaret A VanAmringe, Amber R Wood, Deborah Yokoe, Katherine D Ellingson Journal: Infect […]