Paradoxical Potentiation of Acid-Sensing Ion Channel 3 (ASIC3) by Amiloride via Multiple Mechanisms and Sites Within the Channel

Article: Paradoxical Potentiation of Acid-Sensing Ion Channel 3 (ASIC3) by Amiloride via Multiple Mechanisms and Sites Within the Channel Authors: Daniel S Matasic, Nicholas Holland, Mamta Gautam, David D Gibbons, Nobuyoshi Kusama, Anne M S Harding, Viral S Shah, Peter M Snyder, Christopher J Benson Journal: Front Physiol. 2021 Oct 15;12:750696. Abstract: Acid-Sensing Ion Channels […]

Musculoskeletal sarcoidosis: A single center experience over 15 years

Article: Musculoskeletal sarcoidosis: A single center experience over 15 years Authors: Sanjeev Patil, Carolyn A Hilliard, Masumi Arakane, Sreedevi Koppisetti Jenigiri, Elizabeth H Field, Namrata Singh Journal: Int J Rheum Dis. 2021 Apr;24(4):533-541 Abstract: Background: Musculoskeletal (MSK) sarcoidosis presents with a variety of clinical phenotypes. Four subtypes of MSK sarcoidosis have been identified to date: […]

Urban particulate matter impairs airway-surface-liquid-mediated coronavirus inactivation

Article: Urban particulate matter impairs airway-surface-liquid-mediated coronavirus inactivation Authors: Emma M Stapleton, Jennifer L Welch, Erika A Ubeda, Jinhua Xiang, Joseph Zabner, Ian M Thornell, Matthew W Nonnenmann, Jack T Stapleton, Alejandro P Comellas Journal: J Infect Dis. 2021 Nov 3;jiab545 Abstract: Air pollution particulate matter (PM) is associated with SARS-CoV-2 infection and severity, although […]

What Makes a Great Mentor: Interviews With Recipients of the ATVB Mentor of Women Award

Article: What Makes a Great Mentor: Interviews With Recipients of the ATVB Mentor of Women Award Authors: Hanrui Zhang, Zhen Bouman Chen, Gabrielle Fredman, Delphine Gomez, Isabella M Grumbach, Ngan F Huang, Patricia Kim Phuong Nguyen, Mireille Ouimet, Nadia R Sutton, Elena Aikawa Journal: Arterioscler Thromb Vasc Biol. 2021 Nov;41(11):2641-2647. Highlights: To celebrate the 20th […]

Direct endoscopic placement of percutaneous endoscopic gastrostomies with jejunal extension tubes (PEG-J) using ultra-thin endoscopes – long-term outcomes from a U.S. tertiary referral center

Article: Direct endoscopic placement of percutaneous endoscopic gastrostomies with jejunal extension tubes (PEG-J) using ultra-thin endoscopes – long-term outcomes from a U.S. tertiary referral center Authors: Yazan Hasan, Asad Ali, Amer El Sayed, Avraham Levin, Henning Gerke, Hye Yeon Jhun, Mohamad Mokadem, Rami El Abiad, Randhir Jesudoss, Steven Polyak, Nadav Sahar Journal: Surg Endosc. 2021 […]

Risk of Venous Thromboembolism in Hospitalized Patients with Acute Ischemic Stroke Versus Other Neurological Conditions

Article: Risk of Venous Thromboembolism in Hospitalized Patients with Acute Ischemic Stroke Versus Other Neurological Conditions Authors: Aayushi Garg, Nirav Dhanesha, Amir Shaban, Edgar A Samaniego, Anil K Chauhan, Enrique C Leira Journal: J Stroke Cerebrovasc Dis. 2021 Nov;30(11):106077 Abstract: Background: The mechanism of increased risk of venous thromboembolism (VTE) after acute ischemic stroke (AIS) […]

Relabeling of penicillin drug allergy after evaluation in a drug allergy clinic

Article: Relabeling of penicillin drug allergy after evaluation in a drug allergy clinic Authors: Deanna McDanel, Lyvia Hosch, Kassi D Pham, Abbey Schwery, Karlie Seiler, Amy M Dowden Journal: J Allergy Clin Immunol Pract. 2021 Sep 16;S2213-2198(21)01004-7 Clinical implications: More than 90% of patients after evaluation in a drug allergy clinic had their penicillin allergy […]

Altering Early Life Gut Microbiota Has Long-Term Effect on Immune System and Hypertension in Spontaneously Hypertensive Rats

Article: Altering Early Life Gut Microbiota Has Long-Term Effect on Immune System and Hypertension in Spontaneously Hypertensive Rats Authors: Francois M. Abboud, Michael Z. Cicha, Aaron Ericsson, Mark W. Chapleau, and Madhu V. Singh Journal: Front. Physiol., 29 October 2021 Abstract: Hypertension is regulated by immunological components. Spontaneously hypertensive rats (SHR) display a large population […]

Central venous-to-arterial PCO2 difference as a marker to identify fluid responsiveness in septic shock

Article: Central venous-to-arterial PCO2 difference as a marker to identify fluid responsiveness in septic shock Authors: Boulos Nassar, Mohamed Badr, Nicolas Van Grunderbeeck, Johanna Temime, Florent Pepy, Gaelle Gasan, Laurent Tronchon, Didier Thevenin & Jihad Mallat Journal: Sci Rep 11, 17256 (2021) Abstract: Defining the hemodynamic response to volume therapy is integral to managing critically […]