Ultrasound-guided vascular access in critical illness

Article: Ultrasound-guided vascular access in critical illness Authors: Schmidt GA, Blaivas M, Conrad SA, Corradi F, Koenig S, Lamperti M, Saugel B, Schummer W, Slama M Journal: Intensive Care Med. 2019 Apr;45(4):434-446 Abstract: Over the past two decades, ultrasound (US) has become widely accepted to guide safe and accurate insertion of vascular devices in critically […]

Fn-EDA in the Plasma, but Not Endothelial Cells, Exacerbates Stroke Outcome by Promoting Thrombo-Inflammation

Article: Fn-EDA (Fibronectin Containing Extra Domain A) in the Plasma, but Not Endothelial Cells, Exacerbates Stroke Outcome by Promoting Thrombo-Inflammation Authors: Nirav Dhanesha, Mehul R. Chorawala, Manish Jain, Abhinav Bhalla, Daniel Thedens, Manasa Nayak, Prakash Doddapattar, Anil K. Chauhan Journal: Stroke. 2019 May;50(5):1201-1209 Abstract: Background and Purpose- Cellular Fn-EDA (fibronectin containing extra domain A) is […]

Small Split Pediatric Kidneys to Expand the Donor Pool: An analysis of Scientific Registry of Transplant Recipients (SRTR) Data

Article: Small Split Pediatric Kidneys to Expand the Donor Pool: An analysis of Scientific Registry of Transplant Recipients (SRTR) Data Authors: Manish Suneja, Sarat Kuppachi, Daniel Katz, Lawrence Hunsicker Journal: Transplantation. 2019 Mar 12. doi: 10.1097/TP.0000000000002706. [Epub ahead of print] Abstract: BACKGROUND: Increased use of pediatric deceased donor kidneys could enlarge the deceased donor kidney […]

TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons

Article: TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons Authors: Runping Wang, Yongjun Lu, Michael Z. Cicha, Madhu V. Singh, Christopher J. Benson, Christopher J. Madden, Mark W. Chapleau, and François M. Abboud Journal: JCI Insight. 2019 Mar 7;4(5). pii: 122058 Abstract: The satiety effects and metabolic actions of cholecystokinin (CCK) have […]

Combined FEV1 and FVC Bronchodilator Response, Exacerbations, and Mortality in COPD

Article: Combined FEV1 and FVC Bronchodilator Response, Exacerbations, and Mortality in COPD Authors: Spyridon Fortis, Alejandro Comellas, Barry J Make, Craig P Hersh, Sandeep Bodduluri, Dimitris Georgopoulos, Victor Kim, Gerard J Criner, Mark T Dransfield, and Surya P Bhatt Journal: Ann Am Thorac Soc. 2019 Mar 25. doi: 10.1513/AnnalsATS.201809-601OC. [Epub ahead of print] Abstract: RATIONALE: […]

Donald Zavala: a giant in chest medicine, or Scoping Hannibal

In a just-published piece in Chest as part of the journal’s “Giants in Chest Medicine” series, Joel Kline, MD, and Joseph Zabner, MD, offer an incredible anecdote about Donald C. Zavala, MD, FCCP, Professor Emeritus of Internal Medicine and the department’s first fellow in pulmonary medicine, “at a time,” they write, “when chest physicians primarily focused on [tuberculosis].” […]

Is Homoarginine a Protective Cardiovascular Risk Factor?

Article: Is Homoarginine a Protective Cardiovascular Risk Factor? Authors: Ekaterina S. Karetnikova, Natalia Jarzebska, Alexander G. Markov, Norbert Weiss, Steven R. Lentz, Roman N. Rodionov Journal: Arterioscler Thromb Vasc Biol. 2019 Mar 14:ATVBAHA118312218 Abstract: A series of recent epidemiological studies have implicated the endogenous nonproteinogenic amino acid l-homoarginine as a novel candidate cardiovascular risk factor. […]

Nutrient Composition Comparison between the Low Saturated Fat Swank Diet for Multiple Sclerosis and Healthy U.S.-Style Eating Pattern

Article: Nutrient Composition Comparison between the Low Saturated Fat Swank Diet for Multiple Sclerosis and Healthy U.S.-Style Eating Pattern Authors: Catherine A. Chenard, Linda M. Rubenstein, Linda G. Snetselaar, and Terry L. Wahls Journal: Nutrients. 2019 Mar 13;11(3). pii: E616 Abstract: Multiple sclerosis (MS) is an incurable degenerative disease that attacks the central nervous system. […]