Rapid response teams (RRTs) are highly specialized hospital emergency teams that treat patients who develop a sudden worsening of their clinical condition, which if not treated can be life-threatening. However, prior studies of the effectiveness of RRTs have shown varied results, leading some to suggest these teams are irrelevant, while others have argued they are […]
In Africa, the Middle East, Mexico, Asia, and South America, more than one billion people are at risk of contracting leishmaniasis, a disease spread through sandflies and caused by the parasite Leishmania major, which manifests most commonly as skin lesions but with the potential for more harmful internal damage. Leishmaniasis mainly affects people in tropical […]
Article: Muscle-specific changes in protein synthesis with aging and reloading after disuse atrophy Authors: Benjamin F. Miller, Leslie M. Baehr, Robert V. Musci, Justin J. Reid, Frederick F. Peelor III, Karyn L. Hamilton, Sue C. Bodine Journal: J Cachexia Sarcopenia Muscle. 2019 Jul 16. doi: 10.1002/jcsm.12470. [Epub ahead of print] Abstract: BACKGROUND: Successful strategies to […]
Article: Breast cancer patient preferences for test result communication Authors: Sneha Phadke DO, Mark Vander Weg PhD, Najla Itani MD, Nicole Grogan MD, Timothy Ginader MS, Sarah Mott MS, Bradley McDowell PhD Journal: Breast J. 2019 Jul 12. doi: 10.1111/tbj.13461. [Epub ahead of print] Excerpt: From personal observation in the breast oncology clinic, it appeared […]
Article: Polarized AAVR expression determines infectivity by AAV gene therapy vectors Authors: Bradley A. Hamilton, Xiaopeng Li, Alejandro A. Pezzulo, Mahmoud H. Abou Alaiwa & Joseph Zabner Journal: Gene Therapy volume 26, pages240–249 (2019) Abstract: Adeno-associated virus (AAV) has been investigated to transfer the cystic fibrosis transmembrane conductance regulator (CFTR) to airways. Inhaled AAV2-CFTR in […]
“Infectious disease outbreaks can induce feelings of threat, uncertainty, and loss of control in people, feelings that have been associated with both increased information seeking and the emergence of conspiracy theories,” Aaron Scherer, PhD, associate in General Internal Medicine, said. Consistent with his past studies, Scherer conducted yet another survey-based study assessing the factors that […]
Article: Chromogranin B regulates early-stage insulin granule trafficking from the Golgi in pancreatic islet β-cells Authors: Shelby C. Bearrows, Casey J. Bauchle, McKenzie Becker, Jonathan M. Haldeman, Svetha Swaminathan, Samuel B. Stephens Journal: J Cell Sci. 2019 Jul 1;132(13) Abstract: Chromogranin B (CgB, also known as CHGB) is abundantly expressed in dense core secretory granules […]
I recently spoke at a residents’ noon conference about the basics of manuscript writing. Although residents are encouraged to write and submit papers, it may be a daunting task for those without a lot of writing experience. My goal was to provide tips for writing and organizing a paper, and to help with deciphering some […]
Article: Coronary Spasm and Polymorphic Ventricular Tachycardia One Year After Takotsubo Authors: Noah N. Williford MD, Alexander Mazur MD, Troy Rhodes MD, PhD, Elaine Demetroulis MD, Milena A. Gebska MD, PhD Journal: Mayo Clin Proc Innov Qual Outcomes. 2019 Jun; 3(2): 231–234. Abstract: Stress cardiomyopathy is typically considered to be a disease with a favorable […]
Article: Tau interacts with SHP2 in neuronal systems and in Alzheimer’s disease Authors: Yohan Kim, Guanghao Liu, Chad J. Leugers, Joseph D. Mueller, Meghan B. Francis, Marco M. Hefti, Julie A. Schneider, Gloria Lee Journal: J Cell Sci. 2019 Jun 14. pii: jcs.229054. doi: 10.1242/jcs.229054. [Epub ahead of print] Abstract: Microtubule-associated protein tau, an integral […]