Blocking ceramides with fungi extract reverses diabetes, obesity, in mice

A publication earlier this month in Scientific Reports demonstrates that a key lipid metabolite may be a useful targeting in preventing or even reversing diabetes and many of its comorbidities. Ceramides are a characteristic of obesity, and increased accumulation of these metabolites contributes to glucose and metabolism impairments. In rodents, ceramide degradation prevented and reversed […]

Myeloid Cell PKM2 Deletion Enhances Efferocytosis and Reduces Atherosclerosis

Article: Myeloid Cell PKM2 Deletion Enhances Efferocytosis and Reduces Atherosclerosis Authors: Prakash Doddapattar, Rishabh Dev, Madankumar Ghatge, Rakesh B Patel, Manish Jain, Nirav Dhanesha, Steven R Lentz, Anil K Chauhan Journal: Circ Res. 2022 Apr 29;130(9):1289-1305 Abstract: Background: The glycolytic enzyme PKM2 (pyruvate kinase muscle 2) is upregulated in monocytes/macrophages of patients with atherosclerotic coronary […]

Meet Our APPs: Jessie Alex, ARNP, DNP, FNP-BC, PMHNP-BC

We are pleased to present the next in our weekly series introducing you to Internal Medicine’s Advanced Practice Providers. In addition to sharing information about where they work in the department, we asked them each to tell us a little bit about their “Why” (the sustaining pull for their work) and what relaxes them. (Read […]

Abel elected to National Academy of Sciences

E. Dale Abel, MD, PhD, was named as one of the 120 newly elected members of the National Academy of Sciences last week. Abel is the William S. Adams Distinguished Professor of Medicine, chair, and executive medical director of the Department of Medicine in the David Geffen School of Medicine at UCLA Health, Los Angeles. […]

Association of Nonobstructive Chronic Bronchitis With All-Cause Mortality

Article: Association of Nonobstructive Chronic Bronchitis With All-Cause Mortality Authors: Spyridon Fortis, MD, Zacariah K. Shannon, DC, Crystal J. Garcia, Rodrigo Vazquez Guillamet, MD, Ariel M. Aloe, PhD, Marin L. Schweizer, PhD, Victor Kim, MD, Rajeshwari Nair, PhD Journal: Chest. 2022 DOI:https://doi.org/10.1016/j.chest.2022.02.003 Abstract: Background: The effect of nonobstructive chronic bronchitis (CB) on mortality is unclear. […]

The privilege of educating

The combination of graduation and spring seems appropriate, blooming flowers and all. We are some weeks off from our own graduating trainees finishing but the invitations to celebrate are starting to pop up just like the green shoots in our gardens. The residents’ graduation in early June promises to be just as heartfelt and fun […]

“Always trying to innovate”: a mini Q&A with Manish Suneja, MD

Manish Suneja, MD, is the Vice Chair for Education and Program Director (PD) of the Internal Medicine Residency Program. He sat down with us recently to talk briefly about where the program has been and where it is headed next. You became Program Director in 2014, eight years ago. Who was instrumental in helping you […]

OSTEs slow down, find new focus

Internal Medicine residents learn a variety of skills at Iowa that make them highly sought after as high-caliber clinicians. But what makes them outstanding team members and leaders wherever they go is their refined ability to pass on what they know to others. Effectively teaching others to do what they can forms the core of […]

M4 Student Awards, 2021–22

The William R. Wilson Award The 2020–21 William R. Wilson Award goes to Olivia Chase and Mackenzie Walhof. These two have shown exceptional accomplishment in their clinical work in Internal Medicine. The Wilson Award was created in 1982 to honor the memory of an Internal Medicine faculty member who exemplified the finest in teaching, clinical […]