Rehman publication, career development award advance CF research

Cystic fibrosis (CF) is one of the most common life-shortening inherited disorders. Previous research, some of which was conducted at the University of Iowa, found that mutations in the gene CFTR cause CF. The protein encoded by this gene forms apical membrane chloride and bicarbonate channels in human airway epithelia. Building off of this research, […]

Dai receives career development from Internal Medicine mentors

Dao-Fu Dai, MD, PhD, assistant professor of Pathology and Radiation Oncology, received a three-year, $231,000 Career Development Award from the American Heart Association. Dai will investigate how cystic fibrosis (CF) affects heart rhythm disorder. Although his primary appointment is in a different department, Dai will work under the mentorship of E. Dale Abel, MD, PhD; […]

Welsh receives Kober Medal

Michael Welsh, MD, professor of Pulmonary, Critical Care and Occupational Medicine, received the 2020 Association of American Physicians (AAP) George M. Kober Medal. Joseph Zabner, MD, Director of the Division of Pulmonary, Critical Care and Occupational Medicine, presented the honor to Welsh during the AAP, American Society for Clinical Investigation (ASCI) and American Physician Scientist Association […]

Polgreen receives $3.7M R01

Cystic fibrosis (CF) is one of the most common autosomal recessive genetic disorders in the United States, and it results from deleterious mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Because the disease is autosomal recessive, patients with CF must have two defective copies of the gene. CF heterozygotes, individuals carrying only one […]

Stoltz part of inaugural class of Distinguished Scholars

David Stoltz, MD, PhD, professor in Pulmonary, Critical Care and Occupational Medicine, is one of six researchers named this week to the University of Iowa Health Care Distinguished Scholars Program (DSP). This program aims to support internationally recognized scientists who are leaders in their fields of research. Each of them will receive $200,000 grants per […]

Big data and big discoveries

Happy New Year, Happy 2020! I hope the past couple weeks have been restorative, whether you were able to take a lot or even a little time away from work and for yourself. The turning of the calendar to a new year and a new decade may be an arbitrary time for the establishment of […]

CF research lights up Nashville

Sponsored by the Cystic Fibrosis Foundation, the 33rd North American Cystic Fibrosis Conference (NACFC) was held in Nashville, Tennessee, earlier this month. A number of members of the research program at the University of Iowa made the trip. This included faculty in the adult and pediatric pulmonary divisions, a pediatric endocrinologist, study nurses, pathologists, microbiologists, […]

Thornell receives Gilead grant

Ian Thornell, PhD, Research Assistant Professor, received a two-year, $120,370 grant from the Gilead Sciences Research Scholars Program in Cystic Fibrosis to examine chloride secretion in cells directly and indirectly affected by the disease. Genetic mutations in cystic fibrosis transmembrane conductance regulator (CFTR), an anion channel in the membrane of the airway epithelia, causes cystic […]

Iowa receives continued CFF accreditation

Providers at University of Iowa Health Care learned this week that they have earned continued accreditation from the Cystic Fibrosis Foundation (CFF). The CFF establishes a standard of care based on guidelines developed with leading experts and based on peer-reviewed evidence and research. By adhering to those guidelines, establishing meaningful quality improvement, and undergoing a […]

PBI Convergence Grant Awarded to CF Researchers

A major component of research in the Pappajohn Biomedical Institute (PBI) is to encourage interdisciplinary collaboration and to expose researchers to new ways of looking at problems. This spirit is built into the architecture and layout of each floor of laboratories in the Pappajohn Biomedical Discovery Building, which can find basic scientists working alongside computer […]