Zhang focuses on oncometabolite’s role in heart failure

Yuan Zhang, PhD, associate in Endocrinology and Metabolism, received a three-year, $231,000 Career Development Award from the American Heart Association. Zhang’s project, “2-Hydroxyglutate mediates cardiac remodeling induced by mitochondrial stress,” seeks to understand how cardiac metabolism affects heart function. Zhang is a member of the Abel Laboratory. This is the second of three AHA CDAs […]

Grueter looks for heart failure treatment target in cardiomyocyte behavior

Chad Grueter, PhD, associate professor in Cardiovascular Medicine, received a one-year, $154,500 grant from the NIH’s National Center for Advancing Translational Sciences to understand the role of protein coding gene, Cdk-19, in heart disease. Grueter’s new R03 project, “Cdk-19 Dependent Transcriptional Mechanisms in Cardiac Hypertrophy,” will examine the ways in which Cdk-19/Cdk-8 activity regulates cardiac […]

Boudreau earns third active R01

Ryan Boudreau, PhD, associate professor in Cardiovascular Medicine, received a four-year, $1.5M R01 grant from the National Heart, Lung, and Blood Institute. Boudreau will use this funding to further examine the role of mitoregulin, a protein his team recently discovered, in cardiac biology and disease. Boudreau now holds three R01s, all of which focus on […]

Boudreau receives $1.9M R01

Ryan Boudreau, PhD, assistant professor in Cardiovascular Medicine, was awarded a five-year, $1.9M NIH R01. This funding will support Boudreau’s further investigation of the cardiovascular effects of a genetic variant in SCN5A, the gene that encodes the Nav1.5 sodium channel that provides the required electrical activity to initiate each heartbeat. In a former study, Boudreau’s […]

Heart Failure in the Heartland Symposium Highlights, 10/13-14, 2016

Two days is barely enough to cover a fraction of the facets surrounding one of the world’s leading causes of death. The University of Iowa’s Heart and Vascular Center, together with the Department of Internal Medicine, hosted its eighth annual gathering to address as much as they could. This was the second year that it […]