Threats to mitochondrial respiration in brown fat

The mitochondria are the hidden driver behind the cells that help all parts of the body function as a singular, comprehensive system. Brown fat, which regulates body temperature and total body fat, requires the metabolic mitochondria to burn energy in order to function properly. However, like any other part of the body, certain proteins can […]

Abel to Study Estrogen and Platelet Mitochondria

E. Dale Abel, MD, PhD, has received a two-year, $1.4M NIH grant to explore potential links between estrogen, platelet mitochondria, and increased incidence of thrombosis in females, particularly following estrogen exposure. A successful outcome may identify novel biomarkers that might predict thrombosis risk in this susceptible population. The mitochondrial protein, OPA1, plays an important role in mitochondrial fusion. Previous epidemiological studies had […]

AHA Grants to Internal Medicine

The American Heart Association has recently approved a round of funding for multiple members of the Department. Two Winter 2017 Grant-in-Aid awards each totaling $154,000 are set to begin July 1 and will continue through the end of June 2019. In her project, Dr. Isabella Grumbach, Vice Chair for Research, will focus on how mitochondria […]