Desensitization strategies: is it worth it?

Article: Desensitization strategies: is it worth it? Authors: Sarat Kuppachi, David A. Axelrod Journal: doi: 10.1111/TRI.13532 Abstract: Preformed donor specific antibodies limit access to transplantation for thousands of renal transplant patients. While kidney paired donation offers the best strategy for patients with a living donor, for very highly sensitized patients and those without living donors, […]

Inpatient Fluoroquinolone Stewardship Improves the Quantity and Quality of Fluoroquinolone-prescribing at Hospital Discharge: A Retrospective Analysis among 122 Veterans Health Administration Hospitals

Article: Inpatient Fluoroquinolone Stewardship Improves the Quantity and Quality of Fluoroquinolone-prescribing at Hospital Discharge: A Retrospective Analysis among 122 Veterans Health Administration Hospitals Authors: Hiroyuki Suzuki, MD, Eli N Perencevich, MD, MS, Bruce Alexander, PharmD, Brice E Beck, MA, Michihiko Goto, MD, MSCI, Brian C Lund, PharmD, Rajeshwari Nair, MBBS, PhD, Daniel J Livorsi, MD, […]

Anorexia Nervosa and Osteoporosis: Pathophysiology and Treatment

Article: Anorexia Nervosa and Osteoporosis: Pathophysiology and Treatment Authors: Jeremy Steinman and Amal Shibli-Rahhal Journal: J Bone Metab. 2019 Aug;26(3):133-143. Abstract: Anorexia nervosa (AN) affects 2.9 million people, many of whom experience bone loss and increased fracture risk. In this article, we review data on the underlying pathophysiology of AN-related osteoporosis and possible approaches to […]

Dietary Fatty Acid Saturation Modulates Sphingosine-1-Phosphate-Mediated Vascular Function

Article: Dietary Fatty Acid Saturation Modulates Sphingosine-1-Phosphate-Mediated Vascular Function Authors: Daniel W. Nuno and Kathryn G. Lamping Journal: J Diabetes Res. 2019 Aug 25;2019:2354274 Abstract: Sphingolipids, modified by dietary fatty acids, are integral components of plasma membrane and caveolae that are also vasoactive compounds. We hypothesized that dietary fatty acid saturation affects vasoconstriction to sphingosine-1-phosphate […]

Enhancing glycolysis attenuates Parkinson’s disease progression in models and clinical databases

Article: Enhancing glycolysis attenuates Parkinson’s disease progression in models and clinical databases Authors: Rong Cai, Yu Zhang, Jacob E. Simmering, Jordan L. Schultz, Yuhong Li, Irene Fernandez-Carasa, Antonella Consiglio, Angel Raya, Philip M. Polgreen, Nandakumar S. Narayanan, Yanpeng Yuan, Zhiguo Chen, Wenting Su, Yanping Han, Chunyue Zhao, Lifang Gao, Xunming Ji, Michael J. Welsh, and […]

Effect of Early and Late Interventions with Dietary Oils on Vascular and Neural Complications in a Type 2 Diabetic Rat Model

Article: Effect of Early and Late Interventions with Dietary Oils on Vascular and Neural Complications in a Type 2 Diabetic Rat Model Authors: Lawrence Coppey, Eric Davidson, Hanna Shevalye, Alexander Obrosov, and Mark Yorek Journal: J Diabetes Res. 2019 Aug 7;2019:5020465. Abstract: Aims. Determine the effect of dietary oils enriched in different mono- or polyunsaturated […]

An Investigation of p53 in Skeletal Muscle Aging

Article: An Investigation of p53 in Skeletal Muscle Aging Authors: Scott M. Ebert, Jason M. Dierdorff, David K. Meyerholz, Steven A. Bullard, Asma Al-Zougbi, Austin D. DeLau, Kristin C. Tomcheck, Zachary P. Skopec, George R. Marcotte, Sue C. Bodine, and Christopher M. Adams Journal: J Appl Physiol (1985). 2019 Aug 29. doi: 10.1152/japplphysiol.00363.2019. [Epub ahead […]

Iowa TelePrEP: A Public-Health-Partnered Telehealth Model for Human Immunodeficiency Virus Preexposure Prophylaxis Delivery in a Rural State

Article: Iowa TelePrEP: A Public-Health-Partnered Telehealth Model for Human Immunodeficiency Virus Preexposure Prophylaxis Delivery in a Rural State Authors: Hoth, Angela B. PharmD, MPH; Shafer, Cody; Dillon, Dena Behm PharmD; Mayer, Randy MS, MPH; Walton, George MPH; Ohl, Michael E. MD, MSPH¶ Journal: Sexually Transmitted Diseases: August 2019, 46(8):507–512 Abstract: Background: Access to human immunodeficiency […]