Maintenance of muscle mass in adult male mice is independent of testosterone

Article: Maintenance of muscle mass in adult male mice is independent of testosterone Authors: Arik Davidyan, Suraj Pathak, Keith Baar, Sue C Bodine Journal: PLoS One. 2021 Mar 25;16(3):e0240278. Abstract: Testosterone is considered a potent anabolic agent in skeletal muscle with a well-established role in adolescent growth and development in males. However, the role of […]

Transcatheter Valve Implantation in a Severely Regurgitant Apicoaortic Conduit

Article: Transcatheter Valve Implantation in a Severely Regurgitant Apicoaortic Conduit Authors: Phanicharan A Sistla, Prashob Porayette, Osamah T Aldoss, Sidakpal S Panaich Journal: JACC Cardiovasc Interv. 2021 Mar 22;14(6):e53-e56. Excerpt: A 33-year-old woman with congenital bicuspid aortic stenosis had a complex surgical history, which included aortic valve replacement with a 21-mm Freestyle bioprosthesis (Medtronic, Dublin, […]

Serrated polyp detection rate and advanced adenoma detection rate from a US multicenter cohort

Article: Serrated polyp detection rate and advanced adenoma detection rate from a US multicenter cohort Authors: Jagpal S Klair, Munish Ashat, Dane Johnson, Sumant Arora, Nirmal Onteddu, Jose G Machain Palacio, Ronald Samuel, Mohammad Bilal, Avanija Buddam, Ashutosh Gupta, Alan Gunderson, Praveen Guturu, Kaartik Soota, Subhash Chandra, Arvind R Murali Journal: Endoscopy. 2020 Jan;52(1):61-67. doi: […]

Smooth Muscle Cell-Specific PKM (Pyruvate Kinase M) 2 Promotes Smooth Muscle Cell Phenotypic Switching and Neointimal Hyperplasia

Article: Smooth Muscle Cell-Specific PKM (Pyruvate Kinase M) 2 Promotes Smooth Muscle Cell Phenotypic Switching and Neointimal Hyperplasia Authors: Manish Jain, Nirav Dhanesha, Prakash Doddapattar, Manasa K Nayak, Liang Guo, Anne Cornelissen, Steven R Lentz, Aloke V Finn, Anil K Chauhan Journal: Arterioscler Thromb Vasc Biol. 2021 Mar 11;ATVBAHA121316021. Online ahead of print. Abstract:Objective: The […]

Ratio of Forced Expiratory Volume in 1 second /Slow Vital Capacity (FEV 1/SVC)<0.7 is associated with clinical, functional, and radiologic features of obstructive lung disease in smokers with preserved lung function

Article: Ratio of Forced Expiratory Volume in 1 second /Slow Vital Capacity (FEV 1/SVC)<0.7 is associated with clinical, functional, and radiologic features of obstructive lung disease in smokers with preserved lung function Authors: Spyridon Fortis, Alejandro Comellas, Surya P Bhatt, Eric A Hoffman, MeiLan K Han, Nirav R Bhakta, Robert Paine 3rd, Bonnie Ronish, Richard […]

Comparison of murine behavioural and physiological responses after forced exercise by electrical shock versus manual prodding

Article: Comparison of murine behavioural and physiological responses after forced exercise by electrical shock versus manual prodding Authors: Tahsin Khataei, Sara A Romig-Martin, Anne Marie S Harding, Jason J Radley, Christopher J Benson Journal: Exp Physiol. 2021 Feb 1. doi: 10.1113/EP089117. Online ahead of print. Abstract:New findings: What is the central question of this study? […]

Using race to estimate glomerular filtration and its impact in kidney transplantation

Article: Using race to estimate glomerular filtration and its impact in kidney transplantation Authors: Sarat Kuppachi, Silas P Norman, Krista L Lentine, David A Axelrod Journal: Clin Transplant. 2021 Jan;35(1):e14136. Abstract:Since direct measurement of glomerular filtration rate (GFR) is time-consuming and more expensive, estimated GFR (eGFR) based on measured laboratory values is widely used to […]

Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging

Article: Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging Authors: Courtney Yong, Devon L Moose, Nadine Bannick, Wade R Gutierrez, Marion Vanneste, Robert Svensson, Patrick Breheny, James A Brown, Rebecca D Dodd, Michael B Cohen, Michael D Henry Journal: PLoS One. 2020 Sep […]

Remote Triage by Nurse Practitioners Was Associated With Fewer Subsequent Face

Article: Remote Triage by Nurse Practitioners Was Associated With Fewer Subsequent Face Authors: Peter J Kaboli, Matthew R Augustine, Danielle E Rose, Neetu Chawla, Maria Bouchard, Paul Hebert Journal: J Gen Intern Med. 2021 Jan 26;1-8.  doi: 10.1007/s11606-020-06536-0.  Online ahead of print. Abstract:  Background: In 2015, the Veterans Health Administration (VHA) incorporated nurse practitioners (NPs) into remote triage call centers to supplement […]

Association of Glycolysis-Enhancing α-1 Blockers With Risk of Developing Parkinson Disease

Article: Association of Glycolysis-Enhancing α-1 Blockers With Risk of Developing Parkinson Disease Authors: Jacob E Simmering, Michael J Welsh, Lei Liu, Nandakumar S Narayanan, Anton Pottegård Journal: JAMA Neurol. 2021 Feb 1. doi: 10.1001/jamaneurol.2020.5157. Online ahead of print. Abstract:Importance: Parkinson disease (PD) is a common neurodegenerative disease. A treatment that prevents or delays development of […]