In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy

Article: In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy Authors: Yinwen Cheng, Caitlin D Lemke-Miltner, Wattawan Wongpattaraworakul, Zhaoming Wang, Carlos H F Chan, Aliasger K Salem, George J Weiner, Andrean L Simons Journal: J Immunother Cancer. 2020 Oct;8(2):e000940 Abstract:Background: CMP-001 is a novel Toll-like receptor-9 agonist that consists of an unmethylated […]

Preserved Ratio Impaired Spirometry in a Spirometry Database

Article: Preserved Ratio Impaired Spirometry in a Spirometry Database Authors: Andrei Schwartz, Nicholas Arnold, Becky Skinner, Jacob Simmering, Michael Eberlein, Alejandro P Comellas, Spyridon Fortis Journal: Respir Care September 2020, respcare.07712 Abstract:Background: Spirometry results can yield a diagnosis of normal air flow, air flow obstruction, or preserved ratio impaired spirometry (PRISm), defined as a reduced […]

Development and implementation of a Telenephrology dashboard for active surveillance of kidney disease: a quality improvement project

Article: Development and implementation of a Telenephrology dashboard for active surveillance of kidney disease: a quality improvement project Authors: Melissa L Swee, M Lee Sanders, Kantima Phisitkul, George Bailey, Angie Thumann, Nikki Neuzil, Bharat Kumar, Amy M J O’Shea, Bradley S Dixon Journal: BMC Nephrol. 2020 Oct 6;21(1):424 Abstract:Background: Kidney disease accounts for more than […]

Mentoring minority trainees: Minorities in academia face specific challenges that mentors should address to instill confidence

Article: Mentoring minority trainees: Minorities in academia face specific challenges that mentors should address to instill confidence Authors: Antentor O. Hinton, Jr., Zer Vue, Christina M. Termini, Brittany L. Taylor, Haysetta D. Shuler, Melanie R. McReynolds Journal: EMBO Rep. 2020 Oct 5;21(10):e51269. Excerpt:The art of mentorship was first described in Homer’s Odyssey as the character […]

Lung function of primary cooks using LPG or biomass and the effect of particulate matter on airway epithelial barrier integrity

Article: Lung function of primary cooks using LPG or biomass and the effect of particulate matter on airway epithelial barrier integrity Authors: Emma M Stapleton, Abhilash Kizhakke Puliyakote, Nervana Metwali, Matthew Jeronimo, Ian M Thornell Robert B Manges, Monalisa Bilas, Mohamed Ali Kamal Batcha, Mangaleswari Seeniappan Kumaravel, Kumar Durairaj, Kesavan Karuppusamy, Geetha Kathiresan, Sirajunnisa Abdul […]

Effectiveness of chlorhexidine dressings to prevent catheter-related bloodstream infections. Does one size fit all? A systematic literature review and meta-analysis

Article: Effectiveness of chlorhexidine dressings to prevent catheter-related bloodstream infections. Does one size fit all? A systematic literature review and meta-analysis Authors: Mireia Puig-Asensio, Alexandre R Marra, Christopher A Childs, Mary E Kukla, Eli N Perencevich, Marin L Schweizer Journal: Infect Control Hosp Epidemiol. 2020 Sep 16;1-8. Online ahead of print. Abstract:Objective: To evaluate the […]

Case of relapsing sulfasalazine-induced hypersensitivity syndrome upon re-exposure

Article: Case of relapsing sulfasalazine-induced hypersensitivity syndrome upon re-exposure Authors: Jason Winward, Laurel Lyckholm, Samuel M Brown, Mohamad Mokadem Journal: BMJ Case Rep. 2020 Sep 15;13(9):e235803 Abstract:Sulfasalazine-induced hypersensitivity syndrome (SIHS) is a serious systemic delayed adverse drug reaction that is associated with significant morbidity and mortality. Here, we report the first case, to our knowledge, […]

Mitochondrial pyruvate carriers are required for myocardial stress adaptation

Article: Mitochondrial pyruvate carriers are required for myocardial stress adaptation Authors: Yuan Zhang, Paul V Taufalele, Jesse D Cochran, Isabelle Robillard-Frayne, Jonas Maximilian Marx, Jamie Soto, Adam J Rauckhorst, Fariba Tayyari, Alvin D Pewa, Lawrence R Gray, Lynn M Teesch, Patrycja Puchalska, Trevor R Funari, Rose McGlauflin, Kathy Zimmerman, William J Kutschke, Thomas Cassier, Shannon […]

Endocannabinoid Receptor-1 and Sympathetic Nervous System Mediate the Beneficial Metabolic Effects of Gastric Bypass

Article: Endocannabinoid Receptor-1 and Sympathetic Nervous System Mediate the Beneficial Metabolic Effects of Gastric Bypass Authors: Yuanchao Ye, Marwa Abu El Haija, Donald A. Morgan, Deng Guo, Yang Song, Aaron Frank, Liping Tian, Ruth A. Riedl, Colin M.L. Burnett, Zhan Gao, Zhiyong Zhu, Shailesh K. Shahi, Kasra Zarei, Anne Couvelard, Nicolas Pote ́, Lara Ribeiro-Parenti, […]