Case Studies in Physiology: Untangling the cause of hypoxemia in an obese patient with acute leukemia

Article: Case Studies in Physiology: Untangling the cause of hypoxemia in an obese patient with acute leukemia Authors: Iliya Amaza, Hardik Kalra, Michael Eberlein, Yogesh Jethava, Joseph McDonell, Bobby Wolfe, Michael H Tomasson, Melissa L Bates Journal: J Appl Physiol. 2021 May 6. doi: 10.1152/japplphysiol.00867.2020. Online ahead of print. Abstract:Diagnosing the cause of hypoxemia and […]

Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling

Article: Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling Authors: Manish Jain, Rishabh Dev, Prakash Doddapattar, Shigeyuki Kon, Nirav Dhanesha, Anil K Chauhan Journal: JCI Insight. 2021 May 24;6(10):147134. Abstract:Excessive proliferation of vascular smooth muscle cells (SMCs) remains a significant cause of in-stent restenosis. Integrins, which are heterodimeric transmembrane receptors, play a […]

Risk-Standardized Home Time as a Novel Hospital Performance Metric for Pneumonia Hospitalization Among Medicare Beneficiaries: a Retrospective Cohort Study

Article: Risk-Standardized Home Time as a Novel Hospital Performance Metric for Pneumonia Hospitalization Among Medicare Beneficiaries: a Retrospective Cohort Study Authors: Rajeshwari Nair, Yubo Gao, Mary S Vaughan-Sarrazin, Eli Perencevich, Saket Girotra, Ambarish Pandey Journal: J Gen Intern Med. 2021 Apr 26. doi: 10.1007/s11606-021-06712-w. Online ahead of print. Abstract:Background: The Centers for Medicare & Medicaid […]

Wearable Monitors Facilitate Exercise in Adult and Pediatric Stem Cell Transplant

Article: Wearable Monitors Facilitate Exercise in Adult and Pediatric Stem Cell Transplant Authors: Ethan Pottebaum, Alexa Warmoth, Sabarish Ayyappan, David S Dickens, Yogesh Jethava, Arunkumar Modi, Michael H Tomasson, Lucas J Carr, Melissa L Bates Journal: Exerc Sport Sci Rev. 2021 Apr 22. doi: 10.1249/JES.0000000000000258. Online ahead of print. Abstract:Hematopoietic stem cell transplant (HSCT) is […]

Perilipin2 down-regulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria

Article: Perilipin2 down-regulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria Authors: Akansha Mishra, Siming Liu, Joseph Promes, Mikako Harata, William I. Sivitz, Brian D. Fink, Gourav Bhardwaj, Brian T. O’Neill, Chen Kang, Rajan Sah, Stefan Strack, Samuel B. Stephens, Timothy H. King, Laura Jackson, Andrew S. Greenberg, Frederick Anokye-Danso, Rexford […]

Hand hygiene and the sequence of patient care

Article: Hand hygiene and the sequence of patient care Authors: Nai-Chung Chang, Michael Jones, Heather Schacht Reisinger, Marin L Schweizer, Elizabeth Chrischilles, Margaret Chorazy, W Charles Huskins, Loreen Herwaldt Journal: Infect Control Hosp Epidemiol. 2021 Apr 6;1-6. doi: 10.1017/ice.2021.82. Online ahead of print. Abstract:Objective: To determine whether the order in which healthcare workers perform patient […]

Palliative care consultation in patients with Staphylococcus aureus bacteremia

Article: Palliative care consultation in patients with Staphylococcus aureus bacteremia Authors: Takaaki Kobayashi, Jorge L Salinas, Patrick Ten Eyck, Benjamin Chen, Tomo Ando, Kengo Inagaki, Mohammed Alsuhaibani, Paul G Auwaerter, Ilonka Molano, Daniel J Diekema Journal: Palliat Med. 2021 Apr;35(4):785-792. Abstract:Background: Palliative care consultation has shown benefits across a wide spectrum of diseases, but the […]

Maintenance of muscle mass in adult male mice is independent of testosterone

Article: Maintenance of muscle mass in adult male mice is independent of testosterone Authors: Arik Davidyan, Suraj Pathak, Keith Baar, Sue C Bodine Journal: PLoS One. 2021 Mar 25;16(3):e0240278. Abstract: Testosterone is considered a potent anabolic agent in skeletal muscle with a well-established role in adolescent growth and development in males. However, the role of […]

Transcatheter Valve Implantation in a Severely Regurgitant Apicoaortic Conduit

Article: Transcatheter Valve Implantation in a Severely Regurgitant Apicoaortic Conduit Authors: Phanicharan A Sistla, Prashob Porayette, Osamah T Aldoss, Sidakpal S Panaich Journal: JACC Cardiovasc Interv. 2021 Mar 22;14(6):e53-e56. Excerpt: A 33-year-old woman with congenital bicuspid aortic stenosis had a complex surgical history, which included aortic valve replacement with a 21-mm Freestyle bioprosthesis (Medtronic, Dublin, […]