We are looking forward with excitement to our upcoming annual Research Day on March 2. For fifty years, the Department of Internal Medicine has invited junior faculty, fellows, and students to share the results of their research. This forum has provided feedback, fostered collaboration, and even promoted healthy competition between colleagues. We encourage you to […]
CaMKII inhibition in type II pneumocytes protects from bleomycin-induced pulmonary fibrosis by preventing Ca2+dependent apoptosis
AUTHORS: Christopher J. Winters, Olha Koval, Shubha Murthy, Chantal Allamargot, Sara C. Sebag, John D. Paschke, Omar A. Jaffer, A. Brent Carter, Isabella M. Grumbach JOURNAL: American Journal of Physiology – Lung Cellular and Molecular Physiology, 1 January 2016, 310(1):L86-L94 DOI: 10.1152/ajplung.00132.2015 Abstract: The calcium and calmodulin-dependent kinase II (CaMKII) translates increases in intracellular Ca2+ […]
Research Innovations: CF Mice and Biobanking Consent
We are now nearly a month into the new semester and well into the second month of this new year. I hope that new routines or new resolutions are settling into comfortable habits for you. In my previous post, I promised to discuss interesting advances in research, and I am pleased to highlight a groundbreaking […]
Dare to Look Up
Last month some new banners appeared around Iowa City as part of an initiative by the Office of Research and Development at the University of Iowa. The banners feature faces of members of our UI community from writers like Marilynne Robinson to astronomers like Cornelia Lang. Two members of the Department of Internal Medicine have also […]
Emerging innovative therapeutic approaches targeting PCSK9 to lower lipids
AUTHORS: GPS Shantha and JG Robinson (Dr. Shantha is a Cardiology Fellow) JOURNAL: Clinical Pharmacology & Therapeutics, 99(1):59–71, January 2016 Abstract: Statins are established therapies for cardiovascular disease prevention and ezetimibe has recently been shown to modestly reduce cardiovascular events when added to background statin therapy. Yet here remains a clear unmet need for additional […]
Dale Abel: Cheerleader in chief for diabetes team (Medicine Iowa)
One of E. Dale Abel’s mentors at the University of the West Indies in Kingston, Jamaica, was the School of Medicine chairman, whose strong interest in diabetes and passion for discovery rubbed off on the young scholar. Today, Abel, MD, PhD, is internationally recognized for his research on heart failure in diabetes. Since 2013 he […]
A cystic fibrosis mystery solved (IowaNow)
New research from the University of Iowa answers a question that has vexed cystic fibrosis (CF) researchers for almost 25 years: Why don’t mice with CF gene mutations develop the life-threatening lung disease that affects most people with CF? The research team, led by Michael Welsh, discovered an answer to this long-standing scientific puzzle, and […]
February 2016: Steven Bullard
Steven Bullard, Research Specialist, has spent nearly 30 years in labs around this university, but that was not his original plan. Born and raised in Iowa, Mr. Bullard was preparing for a life after high school as a carpenter, building and remodeling homes. However, a mentor helped him factor into his decision the toll a […]