Allyn L. Mark, MD, Professor Emeritus in the Division of Cardiovascular Medicine, died peacefully on April 3, 2025. The Department extends condolences to his family and friends. Dr. Mark’s impact on the division, the department, and the Carver College of Medicine will be felt long into the future. We are honored to present both the remembrance from his family, followed by comments we solicited from colleagues who worked closely with Dr. Mark and knew him well in his decades at the University of Iowa.

Born on March 13, 1936, to Edward Merle Mark and Dorothy Leigh Mark, Allyn spent a life devoted to scientific discovery, education, and the pursuit of understanding the human heart—both in the physiological and metaphorical sense.

A proud alumnus of the University of Iowa, Dr. Mark earned his bachelor’s degree in 1961 and joined the UI medical faculty in 1967. Over the course of his distinguished career, he served as Director of the Division of Cardiology in the Department of Internal Medicine at the University of Iowa Carver College of Medicine from 1976 to 1995. He was named President of the Association of University Cardiologists from 1994 to 1995, and his contributions were recognized with the Distinguished Mentor Award from the Carver College of Medicine—a reflection of his deep commitment to guiding the next generation of physicians and researchers.

In 1983, Dr. Mark was awarded a prestigious Fulbright Scholarship to study microneurography at the University of Uppsala in Sweden, furthering his groundbreaking work in cardiovascular physiology.

Later in life, he channeled his passion for the history of medicine into the authorship of Pioneers Who Transformed Coronary Disease (2020), a celebration of the people behind the advances he so deeply valued.

Allyn was also a man of deep personal passions. He delighted in travel, the arts, music, and the joys of a shared meal. He was predeceased by his former wife, Lennadore “Sugar” Mark, and his brother Edward Mark.  He is survived by his two children, Curt Leigh Mark (Ann Arbor, MI) and Kristen Mark (Chicago, IL), who carry forward his spirit of curiosity, kindness, and dedication.  We invite anyone who knew and loved Allyn to enjoy a Pagliai’s pizza, and to make a donation to the University of Iowa Stanley Art Museum here.

Please see full comments from colleagues below.

Allyn was fundamental to my academic and clinical career. He trusted me when I needed an advocate, supported me through my fellowship and into my faculty path, and I will never forget it.

– James Hopson, MD

Whether it was during my time as a post-doc or years later when I was attempting to contribute to some multi-investigator project, Dr. Mark was always supportive and encouraging, giving freely of his time. A sharp insightful mind. He led and mentored by example, including for many individuals beyond his own laboratory.

– Frank Faraci, PhD

Dr. Mark was a steadfast mentor and friend. He enhanced the careers and lives of countless trainees. He was never afraid to reinvent himself.

– Peter Snyder, MD

Dr. Allyn Mark had a major impact on my career; the career of his many mentees; and the division, department, and college of medicine. Frank Abboud’s and Allyn’s research is what drew me to the University of Iowa in 1985. Allyn provided valuable input into my research while I was a postdoc in the Abboud lab and after I joined the faculty. Here are some notable memories: (1) the numerous intellectually stimulating PPG and other grant-planning meetings; (2) Me serving as a volunteer subject in one of Allyn’s research studies in which he recorded muscle sympathetic nerve activity from my perineal nerve—a memorable experience!; (3) the honor to have been a co-author on one of Allyn’s publications; and (4) the enthusiasm Allyn displayed at home and at national scientific meetings, both during the scientific sessions and while socializing and dancing in the evenings. Lastly, Allyn Mark was an outstanding clinician scientist and leader. He was a pioneer in studies demonstrating the major role of the nervous system and associated hormones in the pathophysiology of obesity.

– Mark Chapleau, PhD

Allyn was a welcoming friend from the first day I arrived to join the faculty in July of 1973.  He was always there for guidance and comfort.  I and we have lost a dear and talented friend.

– Don Brown, MD

In 1990, my Dad died suddenly within months of Mel Marcus’ death and as I was starting my faculty career at Iowa. I left quickly and on my return met with Allyn. He noted that he was the same age as my mom. He told me that I could call him day or night and he reinforced the promise to provide career guidance and mentorship. He met with me regularly for a while and then as we needed to. He was a strong source of support to me.

– Kevin Dellsperger, MD, PhD

Reading Dr. Mark’s publications as a young internal medicine physician inspired me to gain a deeper understanding of cardiovascular physiology and to pursue a fellowship in cardiovascular diseases. He continued to inspire me as a junior faculty member at Iowa, where his passion for research was infectious. He catalyzed obesity research at Iowa and encouraged us all to come aboard. Through the years, Dr. Mark helped to mentor me as my career progressed and was always willing to give friendly advice. I will miss him dearly.

– Neal Weintraub, MD

Allyn Mark was a pillar of American cardiology and cardiovascular research, a highly regarded thought leader and mentor. Beyond that, he was a longstanding, wise, and energetic leader at the University of Iowa. He will be greatly missed.

– Joseph A. Hill, MD, PhD