Article: Clinical progress note: Phenobarbital in the treatment of alcohol withdrawal syndrome Authors: Thad E Abrams, Matthew V Ronan Journal: J Hosp Med. 2025 Oct;20(10):1094-1098 Abstract: Alcohol withdrawal syndrome (AWS) is a common condition experienced by hospitalized patients. Practice patterns have evolved over time to include the use of phenobarbital, a barbiturate, as an adjunct […]
Before scientists could safely engineer viruses for treatment, researchers in the 1940s and ’50s injected unaltered wild-type viruses into critically ill patients. “It was like the Wild West,” said John Smestad, MD, PhD, third-year Hematology & Medical Oncology fellow. “Doctors would come back with a sample of a virus from a patient who got ill […]
Article: Integrated approaches to reduce alcohol use in people with liver disease: a scoping review and quantitative analysis Authors: Andrea N Weber, Marcus Osman, Laurel Smeins, Sahil Chawla, Mary M Thomas, Stephan Arndt, Nicholas L Bormann Journal: Alcohol and Alcoholism, Volume 60, Issue 6, November 2025 Abstract: Aims: Alcohol-associated liver disease (ALD) and alcohol use […]
Nonbacterial Osteomyelitis, and Comparison to Chronic Rheumatic and Inflammatory Diseases Authors: Aleksander Lenert, Jenna Thomason, Melanie H Smith, Helena Abodeely, Sandy D Hong, Courtney E Kremer, Petar S Lenert, T Shawn Sato, Sandra Hansmann, Melissa Oliver, Yongdong Dan Zhao, Jonathan Templin, Mary Vaughan-Sarrazin, Robyn Domsic, Daniel H Solomon, Polly J Ferguson Journal: J Rheumatol. 2025 […]
Article: Sex and body size disparities under MELD 3.0: Evaluation of persisting gaps in liver transplant access Authors: Tomohiro Tanaka, Dan M Shane, Jennifer C Lai Journal: Hepatology. 2025 Oct 16. doi: 10.1097/HEP.0000000000001581. Online ahead of print Abstract: Background: The July 2023 implementation of MELD3.0 aimed to address longstanding sex disparities in liver transplant (LT) […]
Article: Occupational Health and Safety on the Chopping Block — What’s at Stake? Authors: Andrew T. Gabrielson, MD and Claudia Corwin, MD, MPH Journal: N Engl J Med 2025;393:1353-1355 Excerpt: In an era of labor shortages and rising workplace-injury costs, the U.S. government has taken steps to dismantle the bedrock research agency charged with safeguarding […]
Article: Medical Students’ Attitudes and Experiences Regarding Persuasion of Patients by Physicians: Clarifying the Ethics of Shared Decision Making Authors: John Muckler, James C Thomas, Laura Shinkunas, Lauris C Kaldjian Journal: J Gen Intern Med. 2025 Sep 4. doi: 10.1007/s11606-025-09807-w. Online ahead of print Abstract: Background: Ethical principles of autonomy and beneficence guide clinical decision […]
Article: Proinflammatory Cytokines Mediate Pancreatic β-Cell-Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition Authors: Sandra E Blom, Palin R Narsian, Riley M Behan-Bush, James A Ankrum, Ling Yang, Samuel B Stephens Journal: Diabetes. 2025 Sep 4:db250132. Online ahead of print. Abstract: Type 1 diabetes (T1D) is caused by the selective autoimmune ablation of pancreatic […]
Article: Junctophilin-2 Regulates Store-Operated Calcium Entry to Drive Cardiac Fibroblast Activation, Fibrotic Repair, and Angiogenesis After Myocardial Infarction Authors: Jinxi Wang, Daniela Sarahi Yang Bennett, Emma J Echard, Biyi Chen, Grace Ciampa, Weiyang Zhao, Qian Shi, Jin-Young Yoon, Robert M Weiss, Chad E Grueter, Duane D Hall, Barry London, Long-Sheng Song Journal: Circulation. 2025 Sep […]
Article: Avian Influenza Virus: The Next Pandemic? Author: Patricia L Winokur Journal: Trans Am Clin Climatol Assoc. 2025:135:87-98 Abstract: Novel avian influenza viruses continue to circulate in animal species around the world and show a propensity to reassort and acquire virulence factors, which raises the concern that these viruses may adapt to humans. Pandemic preparedness […]