Inside SAPHO-CNO: Lenert’s exploration of disease activity and genetic influences

Rheumatologist Aleksander Lenert, MD, MS, FRCPC, recently received a five-year, mentored, and patient-oriented K23 research career development award in the amount of $837,000 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) entitled, “Investigating Disease Activity, Bone Damage and Interleukin-1 Genes in Adult SAPHO Syndrome and Chronic Nonbacterial Osteomyelitis.” The research will […]

Big data expands understanding even in rare diseases

Adult-onset Still’s disease (AOSD) is a rare autoinflammatory disease driven by the innate immune system leading to clinical manifestations of fever, rash, and arthritis. Additionally, AOSD patients can present with severe complications at onset including macrophage activation syndrome (MAS) and lung disease. Because large prospective cohorts of AOSD patients are lacking, research into long-term clinical […]