The Chaurasia Lab, led by Bhagirath Chaurasia, MSc, PhD, assistant professor in the Division of Endocrinology & Metabolism, has continued to explore emerging targets to reduce obesity and treat metabolic conditions. Their recent publication, “Ceramide-induced FGF13 impairs systemic metabolic health,” appears in Cell Metabolism and contributes to the group’s history of groundbreaking research in the […]
Five Internal Medicine pre- and post-doctoral researchers were honored with American Heart Association (AHA) fellowship awards. Gokul Patil, MS, PhD; Himani Thakkar, PhD; Vinnyfred Vincent, PhD; Jayashree Jena, PhD; and Ayushi Sood each were notified of their acceptances in December 2024. To be eligible, predoctoral AHA award applicants are required to be full-time students enrolled […]
Bhagirath Chaurasia, PhD, assistant professor in the Division of Endocrinology and Metabolism and a member of the Fraternal Order of Eagles Diabetes Research Center, has received a three-year, $450,000 grant from the Roy J. Carver Charitable Trust. The grant will fund Chaurasia’s research program “Role of serine in development of obesity-induced insulin resistance.” Serine—a non-essential […]
A publication earlier this month in Scientific Reports demonstrates that a key lipid metabolite may be a useful target in preventing or even reversing diabetes and many of its comorbidities. Ceramides are a characteristic of obesity, and increased accumulation of these metabolites contributes to glucose and metabolism impairments. In rodents, ceramide degradation prevented and reversed […]
Bhagirath Chaurasia, PhD, assistant professor in the Division of Endocrinology and Metabolism, has recieved a four-year, $545,100 Junior Faculty Development Award from the American Diabetes Association (ADA). The grant will fund Chaurasia’s exploration of the mechanisms by which ceramides regulate adipocyte overload. Chaurasia described his current research: Ceramides are fat molecules that accumulate in individuals […]
Thermogenic adipocytes are specialized cells capable of converting chemical energy into heat and regulating body temperature. However, aging and weight gain can deplete thermogenic adipocytes and increase insulin resistance. Bhagirath Chaurasia, PhD, assistant professor in Endocrinology and Metabolism, aimed to determine the mechanisms behind this correlation in a study recently published in Molecular Metabolism. “Thermogenic adipocyte quantity […]